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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCD
All Species:
9.09
Human Site:
S302
Identified Species:
15.38
UniProt:
Q05655
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.46
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05655
NP_006245.2
676
77505
S302
T
Q
R
A
S
R
R
S
D
S
A
S
S
E
P
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
R305
T
Q
Q
A
R
C
L
R
D
T
E
Q
I
F
R
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
S766
T
Q
R
A
S
R
R
S
D
S
A
S
S
E
P
Dog
Lupus familis
XP_849292
706
81555
R305
T
Q
Q
A
R
C
L
R
D
T
E
H
I
F
R
Cat
Felis silvestris
Mouse
Mus musculus
P28867
674
77529
R300
Q
V
T
Q
R
S
S
R
K
L
D
T
T
E
S
Rat
Rattus norvegicus
P09215
673
77502
R300
Q
V
T
Q
K
A
S
R
K
P
E
T
P
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
P326
G
L
T
N
P
T
K
P
G
T
T
L
L
P
L
Chicken
Gallus gallus
NP_001006133
699
80179
S300
S
Q
K
S
T
R
R
S
D
S
G
S
V
E
N
Frog
Xenopus laevis
NP_001084460
683
78181
K301
S
M
K
S
S
T
R
K
S
D
S
G
L
D
N
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
A237
G
S
R
E
S
G
K
A
V
S
S
L
G
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83099
671
76314
R288
K
R
G
A
R
E
A
R
D
S
P
S
T
P
P
Honey Bee
Apis mellifera
XP_394743
624
71014
S247
L
Q
S
L
K
R
G
S
T
F
I
Y
D
F
H
Nematode Worm
Caenorhab. elegans
P34722
704
80280
N328
N
G
E
T
S
K
N
N
G
S
L
P
N
K
L
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
W240
E
A
V
Y
E
P
L
W
T
T
D
G
G
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.7
58.5
63.5
N.A.
90.3
89.5
N.A.
63.7
82.4
81.4
33.2
N.A.
46.7
45.2
47.1
49.1
Protein Similarity:
100
76.7
59
77.6
N.A.
95.4
95.2
N.A.
77.9
89.9
89.5
50.8
N.A.
61.9
61.3
64.7
63.6
P-Site Identity:
100
26.6
100
26.6
N.A.
6.6
6.6
N.A.
0
53.3
13.3
20
N.A.
33.3
20
13.3
6.6
P-Site Similarity:
100
40
100
40
N.A.
20
13.3
N.A.
13.3
80
46.6
40
N.A.
46.6
20
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
36
0
8
8
8
0
0
15
0
0
0
0
% A
% Cys:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
43
8
15
0
8
8
0
% D
% Glu:
8
0
8
8
8
8
0
0
0
0
22
0
0
36
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
22
0
% F
% Gly:
15
8
8
0
0
8
8
0
15
0
8
15
15
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
15
0
8
% I
% Lys:
8
0
15
0
15
8
15
8
15
0
0
0
0
8
0
% K
% Leu:
8
8
0
8
0
0
22
0
0
8
8
15
15
8
15
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
8
8
0
0
0
0
8
0
15
% N
% Pro:
0
0
0
0
8
8
0
8
0
8
8
8
8
22
29
% P
% Gln:
15
43
15
15
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
22
0
29
29
29
36
0
0
0
0
0
0
15
% R
% Ser:
15
8
8
15
36
8
15
29
8
43
15
29
15
0
8
% S
% Thr:
29
0
22
8
8
15
0
0
15
29
8
15
15
0
8
% T
% Val:
0
15
8
0
0
0
0
0
8
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _